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Insulin Sensitivity Regulation

Meaning

Insulin sensitivity regulation is the complex, homeostatic physiological process governing the degree of responsiveness of peripheral target cells, particularly in muscle, adipose, and liver tissue, to the action of the anabolic hormone insulin. Optimal regulation ensures that a normal, secreted amount of insulin can effectively promote the uptake of glucose from the bloodstream and suppress excessive hepatic glucose production. Maintaining this precise sensitivity is paramount for metabolic health, preventing chronic hyperglycemia, and mitigating the long-term risk of developing type 2 diabetes.