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Insulin Sensitivity Measurement

Meaning

Insulin Sensitivity Measurement is a diagnostic procedure used to quantify how effectively an individual’s cells respond to the signaling action of insulin, specifically regarding glucose uptake and utilization. High sensitivity indicates that a small amount of insulin is sufficient to manage blood glucose, reflecting excellent metabolic health. Conversely, low sensitivity, or insulin resistance, requires the pancreas to produce excessive insulin to maintain glucose control, which is a precursor to metabolic syndrome and type 2 diabetes. This measurement is a cornerstone of personalized metabolic and longevity medicine.