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Insulin Sensitivity Gain

Meaning

Insulin Sensitivity Gain denotes a clinically desirable improvement in the responsiveness of peripheral tissues, such as muscle, fat, and liver cells, to the circulating hormone insulin. This gain means that a lower concentration of insulin is required to achieve an optimal metabolic effect, primarily the uptake and utilization of glucose. Enhanced insulin sensitivity is a cornerstone of metabolic health, directly correlating with reduced risk of type 2 diabetes, cardiovascular disease, and systemic inflammation, which are all significant drivers of age-related decline.