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Insulin Resistance Hormonal Impact

Meaning

Insulin Resistance Hormonal Impact refers to the pervasive, multi-systemic disruption of endocrine function that inevitably follows reduced cellular sensitivity to insulin. Beyond the primary impairment of glucose metabolism, this condition profoundly alters the production, transport, and action of other critical hormones, including sex steroids, thyroid hormones, and adrenal glucocorticoids. The resultant widespread hormonal dysregulation is a central pathophysiological driver of metabolic syndrome, chronic inflammation, and various age-related pathologies.