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Insulin Resistance Genes

Meaning

Insulin Resistance Genes refer to specific genetic loci or single nucleotide polymorphisms (SNPs) within the human genome that are scientifically associated with an increased susceptibility to developing insulin resistance. These genes encode proteins involved in various aspects of glucose metabolism, insulin signaling transduction, and adipocyte function. While lifestyle and environment are major determinants, inherited variations in these genes, such as PPARG, TCF7L2, and IRS-1, can significantly modify an individual’s predisposition to metabolic syndrome and Type 2 Diabetes Mellitus. Identifying these genetic markers allows for a highly personalized, preventative approach to metabolic health and longevity.