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Insulin Resistance Estimation

Meaning

Insulin Resistance Estimation is the clinical or laboratory-based quantification of the degree to which a patient’s cells fail to respond effectively to the signaling action of insulin, despite adequate or elevated circulating insulin levels. This condition, a precursor to type 2 diabetes and a core component of metabolic syndrome, signifies impaired glucose uptake and utilization by muscle, fat, and liver cells. Estimation methods range from simple clinical predictors to complex mathematical models derived from glucose and insulin measurements. Accurate estimation is vital for early intervention to prevent cascading metabolic and cardiovascular complications.