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Insulin Receptor Responsiveness

Meaning

Insulin Receptor Responsiveness describes the degree to which a cell’s insulin receptors efficiently and effectively transduce the signal of insulin binding into the appropriate intracellular metabolic action. This is a critical measure of cellular sensitivity to the hormone, which is paramount for the proper regulation of blood glucose and overall energy metabolism. A diminished responsiveness is clinically termed insulin resistance, a key precursor to metabolic syndrome and type 2 diabetes. Optimal responsiveness is a hallmark of metabolic health and vitality.