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Insulin-Growth Hormone Relationship

Meaning

The Insulin-Growth Hormone Relationship describes the complex, often antagonistic, interplay between two primary metabolic hormones, insulin and growth hormone (GH), in regulating nutrient partitioning, glucose homeostasis, and tissue anabolism. While both hormones are anabolic, their immediate effects on blood sugar are counter-regulatory: insulin lowers glucose, and GH tends to raise it by inducing insulin resistance in peripheral tissues. Understanding this delicate balance is central to managing metabolic health and body composition.