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Insulin and Skin

Meaning

Insulin and skin describes the interconnected physiological relationship where the pancreatic hormone insulin, primarily known for regulating glucose metabolism, also exerts significant trophic and pathological effects on the integumentary system. High levels of circulating insulin, a state known as hyperinsulinemia, can directly stimulate the proliferation of keratinocytes and fibroblasts, leading to various dermatological manifestations. This connection is clinically relevant as skin changes can often serve as early, visible indicators of underlying metabolic dysfunction and insulin resistance. Recognizing these signs is crucial for proactive intervention in hormonal health.