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Inositol Bioavailability

Meaning

Inositol bioavailability refers to the degree and rate at which myo-inositol, or related inositol stereoisomers, is absorbed from the gastrointestinal tract and becomes available at the site of its intended biological action, particularly within target cells. This measure is a critical determinant of the efficacy of inositol supplementation, as it influences its capacity to act as a secondary messenger for hormones like Follicle-Stimulating Hormone (FSH) and insulin. High bioavailability ensures that a sufficient concentration of the compound reaches the cellular level to modulate insulin signaling and ovarian function, which is particularly relevant in conditions like Polycystic Ovary Syndrome (PCOS). Differences in formulation and concurrent nutrient intake can significantly impact this metric.