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Injection Site Pharmacokinetics

Meaning

Injection Site Pharmacokinetics refers to the study of the absorption, distribution, metabolism, and excretion, or ADME, profile of a therapeutic agent specifically from its localized site of administration, such as subcutaneous or intramuscular tissue. This sub-discipline of pharmacokinetics is critical for non-intravenous drug delivery, as the physical properties of the injection site tissue directly govern the rate and extent to which the active substance reaches the systemic circulation. Understanding this process is essential for designing effective dosing regimens for injectable hormonal and peptide therapies.