The intricate process by which biological molecules, including hormones, neurotransmitters, cytokines, and growth factors, transmit regulatory instructions between cells, tissues, and organs to coordinate systemic function. This signaling is the foundation of all physiological communication, dictating cellular behavior, gene expression, and homeostatic balance. Understanding the fidelity of this process is paramount in clinical practice.
Origin
This concept is a modern, high-level interpretation of classical endocrinology and cell biology, where the chemical messengers are conceptualized as ‘information molecules’ carrying data within the biological network. It emphasizes the communicative role of these substances.
Mechanism
The mechanism relies on the specific binding of an information molecule to its cognate receptor on the target cell surface or within the cytoplasm. This binding initiates an intracellular signal transduction cascade, ultimately altering enzyme activity or gene transcription. The fidelity and speed of this signaling are highly dependent on receptor density and the availability of second messengers.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.