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Inflammatory Mediator Differences

Meaning

Inflammatory Mediator Differences describe the clinically significant variations in the type, concentration, and activity of pro- and anti-inflammatory signaling molecules, such as cytokines and chemokines, between individuals or across different physiological states. These differences are crucial in hormonal health, as chronic low-grade inflammation significantly impairs insulin signaling, disrupts the HPA axis, and alters sex hormone metabolism. Understanding these variances allows for highly personalized anti-inflammatory strategies. The individual’s inflammatory signature dictates their vulnerability to chronic disease.