The continuous, clinical and biological monitoring of key signaling proteins, specifically inflammatory cytokines, that mediate and regulate immune and inflammatory responses throughout the body. Effective surveillance is critical for early detection of chronic low-grade inflammation, a silent driver of numerous age-related and metabolic diseases. It involves quantitative assessment of markers like C-reactive protein and interleukins to guide intervention.
Origin
This term is derived from immunology and clinical pathology, combining the key inflammatory mediators, “cytokines,” with the military and medical term “surveillance,” which implies vigilant, continuous monitoring. It highlights the importance of inflammation as a central, measurable biomarker in modern preventative medicine.
Mechanism
Cytokine surveillance quantifies the concentration of pro-inflammatory signals, such as IL-6 and TNF-α, which are often elevated in states of chronic stress, obesity, or hormonal imbalance. By identifying and tracking these markers, clinicians can implement targeted interventions to quench systemic inflammation, thereby protecting endothelial function, improving insulin sensitivity, and preserving neurocognitive health. This process restores immunological balance.
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