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Inflammatory Cytokine Persistence

Meaning

The sustained elevation of pro-inflammatory signaling proteins, known as cytokines (e.g., IL-6, TNF-alpha, IL-1 beta), in the systemic circulation or local tissues beyond the acute phase of an injury or infection. This persistence signifies a state of chronic, low-grade inflammation, which is a major driver of metabolic dysfunction and endocrine resistance. This is a critical biomarker for assessing systemic health and the risk of age-related diseases.