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Inflammatory Cytokine Downregulation

Meaning

Inflammatory Cytokine Downregulation is the targeted physiological or therapeutic process of actively reducing the synthesis, secretion, and biological activity of pro-inflammatory signaling proteins, such as Interleukin-6 and Tumor Necrosis Factor-alpha. This is a critically important clinical objective in managing chronic low-grade inflammation, which is now strongly implicated as a root cause in nearly all age-related and metabolic diseases. Achieving effective downregulation is central to restoring metabolic balance, enhancing tissue repair, and improving systemic health outcomes.