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Inflammatory Cytokine Decrease

Meaning

Inflammatory Cytokine Decrease refers to the clinical objective of reducing the circulating levels of pro-inflammatory signaling proteins, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α), which are associated with chronic low-grade inflammation and contribute to metabolic and endocrine dysfunction. Sustained elevation of these cytokines can interfere with insulin signaling, impair thyroid hormone conversion, and disrupt the HPA axis, accelerating aging and disease progression. Achieving this decrease is a key therapeutic goal for improving systemic health and hormonal sensitivity.