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Inflammaging Cognitive Impact

Meaning

Inflammaging Cognitive Impact describes the detrimental effect of chronic, low-grade, sterile, and systemic inflammation—a process termed “inflammaging”—on the structural integrity and functional capacity of the central nervous system. This persistent inflammatory state, characterized by elevated circulating pro-inflammatory cytokines, accelerates neurodegenerative processes and is a significant non-traditional risk factor for age-related cognitive decline. It represents a key, critical convergence point between immunology and neuroscience in the study of aging.