Skip to main content

Inflammaging Cascade Dampening

Meaning

Inflammaging Cascade Dampening refers to the strategic clinical approach aimed at mitigating the chronic, low-grade, sterile inflammation that accumulates with chronological aging, often termed “inflammaging.” This persistent inflammatory state, characterized by elevated circulating pro-inflammatory cytokines, directly impairs cellular signaling fidelity, mitochondrial function, and accelerates endocrine decline. Dampening this cascade is essential for promoting healthspan extension and improving tissue responsiveness to hormonal signals. It addresses the systemic background noise impeding optimal physiology.