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Individual Genetic Variability

Meaning

The inherent differences in the genetic code, or genome, among individuals within the human population, which result in variations in biological traits, disease susceptibility, and responses to environmental factors and pharmacological agents. This variability includes single nucleotide polymorphisms (SNPs) and copy number variations that influence the structure and function of hormone receptors, metabolic enzymes, and drug transporters. Recognizing this factor is paramount for personalizing hormonal therapy and optimizing clinical outcomes.