Skip to main content

Immunometabolism Interplay

Meaning

Immunometabolism Interplay describes the complex, bidirectional relationship and functional crosstalk between the immune system and metabolic pathways within the body. This field recognizes that immune cells, like all cells, rely on metabolic processes for energy and function, and conversely, metabolic states—such as nutrient excess or deficiency—profoundly influence immune cell activation, differentiation, and inflammatory output. This interaction is critical for understanding chronic low-grade inflammation that underpins conditions like insulin resistance and accelerated aging.