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Immunogenicity Prediction

Meaning

Immunogenicity Prediction is the sophisticated computational and biological process of assessing the likelihood that a therapeutic agent, particularly a peptide or protein-based hormone, will provoke an unwanted immune response in a human patient. This predictive analysis is crucial in the hormonal health space, especially for bio-identical hormones or peptide therapies, as an immune reaction can lead to the formation of neutralizing antibodies, reducing the drug’s efficacy or causing adverse reactions. Accurate prediction allows for the design of safer, less antigenic molecules, thereby maximizing therapeutic benefit and patient safety.