What is the Origin of Immune System Rejuvenation?

Drawing from immunosenescence research, this concept applies principles of regeneration to the lymphoid organs and peripheral immune cell populations. Rejuvenation implies actively reversing the functional decay observed in older immune systems.

What is the Mechanism of Immune System Rejuvenation?

This is supported by optimizing the hormonal environment, as factors like DHEA and certain growth factors directly influence T-lymphocyte maturation and cytotoxic activity within the thymus and secondary lymphoid tissues. Furthermore, reducing systemic inflammatory cytokines frees up immune resources, allowing for more vigorous responses to novel challenges.

Immune System Rejuvenation

Meaning

Immune System Rejuvenation refers to the targeted clinical objective of restoring the functional competence and responsiveness of the adaptive and innate immune components, which often decline due to factors like thymic involution or chronic inflammation. This rejuvenation is critical for effective pathogen surveillance and longevity.