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Immune System Homeostasis

Meaning

Immune System Homeostasis refers to the dynamic, self-regulating state of balance within the host’s defense mechanisms, characterized by the precise ability to mount an appropriate and effective immune response to genuine pathogenic threats while simultaneously maintaining strict self-tolerance and preventing excessive, damaging chronic inflammation. This essential equilibrium is critical for long-term health and vitality, as chronic low-grade inflammation, often termed immunosenescence, is a key recognized driver of age-related diseases and systemic hormonal dysregulation. Achieving this fine-tuned state requires intricate and constant communication between the innate and adaptive immune components.