A therapeutic approach designed to deliberately adjust or fine-tune the activity of the immune system, either by suppressing an overactive response or stimulating a deficient one, to restore immunological homeostasis. In the context of longevity, the focus is often on reducing chronic, sterile inflammation (inflammaging) and enhancing immune surveillance against senescent and malignant cells. This personalized intervention aims to optimize the immune system’s delicate balance.
Origin
A broad clinical term originating from immunology and pharmacology, encompassing a range of interventions aimed at altering the body’s defensive system. The “Modulation” aspect implies a nuanced, targeted adjustment rather than a simple, blunt suppression or activation.
Mechanism
The therapy mechanism can involve the use of specific agents, such as cytokines, hormones, or immunonutritionals, that interact with immune cell receptors and signaling pathways. For example, certain hormones influence the balance between pro- and anti-inflammatory cytokines, reducing systemic inflammatory load. By restoring an appropriate and responsive immune profile, this therapy supports tissue repair and reduces the chronic stress that drives age-related decline.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.