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Immune Hypersensitivity

Meaning

Immune hypersensitivity, in a clinical context, describes an exaggerated or inappropriate immune response to an antigen that is typically harmless to the body, resulting in tissue damage or systemic pathology. In hormonal health, this is particularly relevant in autoimmune endocrinopathies, such as Hashimoto’s thyroiditis or Type 1 diabetes, where the immune system mistakenly attacks and destroys endocrine tissue. These reactions are classified into four distinct types based on the underlying immunological mechanism, each requiring a specific diagnostic and therapeutic approach. Managing this condition is critical for preserving endocrine function and patient quality of life.