Skip to main content

IGFBP-3

Meaning

IGFBP-3, or Insulin-like Growth Factor-Binding Protein 3, is the principal carrier protein for circulating Insulin-like Growth Factor 1 (IGF-1) in the bloodstream. Its primary clinical role is to modulate the bioavailability and half-life of IGF-1, thereby regulating systemic growth and anabolic signaling. Measuring its concentration provides insight into overall somatotropic axis activity.