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IGF-I Concentration Correlation

Meaning

This refers to the clinical assessment of the statistical and physiological relationship between the circulating levels of Insulin-like Growth Factor-I (IGF-I) and the functional status of the somatotropic axis. IGF-I concentration serves as a reliable, integrated marker of Growth Hormone (GH) secretory output over a period of time. Because GH is released in a highly pulsatile manner, a single GH measurement is often unreliable, making the stable, long-acting IGF-I concentration a crucial proxy for overall GH action. A strong correlation indicates a healthy GH-IGF-I signaling cascade.