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IGF-1 Somatotropin Regulation

Meaning

This describes the intricate neuroendocrine control system that governs the production and circulating levels of Insulin-like Growth Factor-1 (IGF-1) through the pituitary hormone Somatotropin, also known as Growth Hormone (GH). Somatotropin, released from the pituitary, stimulates the liver to produce IGF-1, which then acts as the primary mediator of many of GH’s anabolic and growth-promoting effects. This axis is central to metabolism, body composition, and tissue repair. Its functional integrity is crucial for tissue maintenance across the lifespan.