Question 1

What is the Meaning of IGF-1 Serum Concentration?

Accepted Answer

IGF-1 Serum Concentration refers to the measurable level of Insulin-like Growth Factor 1 circulating in the bloodstream, a key anabolic peptide hormone primarily produced by the liver in response to Growth Hormone (GH) stimulation. This concentration serves as the most reliable clinical biomarker for overall Growth Hormone status, reflecting the integrated GH secretion over the preceding 24 hours. IGF-1 is a critical mediator of cell proliferation, tissue growth, and metabolic regulation, with its concentration being a significant indicator of metabolic health and biological aging.

Question 2

What is the Origin of IGF-1 Serum Concentration?

Accepted Answer

The term combines the abbreviation for the peptide hormone, IGF-1, with "serum concentration," denoting the quantifiable amount found in the non-cellular component of blood. IGF-1 was named for its structural similarity to insulin and its powerful growth-promoting effects. Its clinical utility as a reliable surrogate marker for the pulsatile and difficult-to-measure GH was established through decades of pediatric and adult endocrinology research.

Question 3

What is the Mechanism of IGF-1 Serum Concentration?

Accepted Answer

The mechanism of action is part of the integrated GH-IGF-1 axis. Growth Hormone, released from the pituitary gland, travels through the circulation to the liver, where it binds to specific receptors, stimulating the synthesis and release of IGF-1. IGF-1 then acts in an endocrine and paracrine fashion, binding to its own tyrosine kinase receptors on target cells to initiate intracellular signaling pathways. These pathways promote protein synthesis and inhibit apoptosis, driving the anabolic and reparative functions throughout the body.

IGF-1 Serum Concentration

Meaning

Origin

Mechanism

Provided by the clinical team
at 4Ever Young Miami Dadeland

-15% ∞ HRTIO15

Your protocol begins with a conversation.

Visit

Schedule Appointment

About

Med & Wellness

4Ever Young Miami Dadeland

Communication

+1 786-529-6686

Email Us

Opening Hours