What is the Origin of IGF-1 Neural Support?

This term is rooted in the study of the Growth Hormone/IGF-1 axis, specifically recognizing the non-metabolic, paracrine, and endocrine actions of IGF-1 within the specialized environment of the brain. The brain is recognized as both a source and a major target for this powerful peptide.

What is the Mechanism of IGF-1 Neural Support?

IGF-1 acts by binding to its specific receptor, initiating intracellular signaling cascades that actively inhibit neuronal apoptosis, stimulate the formation of new synapses, and promote the health of myelin sheaths. The level of neural support is intrinsically linked to systemic growth hormone status, demonstrating a clear endocrine influence on neurological resilience and repair capacity, particularly in the hippocampus.

IGF-1 Neural Support ∞ Area

IGF-1 Neural Support

Meaning

IGF-1 Neural Support refers to the critical, multifaceted function of Insulin-like Growth Factor 1 in promoting the structural integrity, survival, and functional plasticity of neurons and supporting glial cells within the central nervous system. As a key neurotrophic agent, IGF-1 mediates many of the brain’s processes for growth, repair, and protection against cellular insults. This action is essential for maintaining cognitive reserve throughout the lifespan.