Skip to main content

IGF-1 Messenger

Meaning

The IGF-1 Messenger, or Insulin-like Growth Factor 1, is a crucial polypeptide hormone primarily synthesized by the liver in response to Growth Hormone (GH) stimulation, acting as the principal mediator of GH’s anabolic effects. This messenger molecule is responsible for stimulating systemic growth, promoting cellular proliferation, and inhibiting apoptosis across nearly all tissues, including muscle, bone, and cartilage. Clinically, IGF-1 levels are a robust indicator of the overall functional status of the Growth Hormone axis and are strongly correlated with tissue repair capacity and metabolic health. It is a vital component of the body’s regenerative machinery.