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IGF-1 Contraindication

Meaning

An IGF-1 Contraindication refers to a specific, pre-existing medical condition or state that makes the therapeutic administration of Insulin-like Growth Factor 1 (IGF-1) or growth hormone (GH) absolutely inadvisable due to a significant and unacceptable risk of clinical harm. Because IGF-1 is a potent mitogenic agent that actively promotes cell division and growth, its use is strictly prohibited in patients with any active malignancy or known intracranial lesion. This definitive restriction is paramount for maintaining patient safety in the context of growth factor therapies.