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Hypoxia-Inducible Factor

Meaning

Hypoxia-Inducible Factor, or HIF, is a highly conserved, pivotal transcription factor protein complex that serves as the cell’s master regulator for adapting to conditions of low oxygen, known as hypoxia. In the clinical context of hormonal health, HIF critically orchestrates the expression of numerous genes involved in essential physiological processes, including glucose metabolism, the formation of new blood vessels, or angiogenesis, and the production of red blood cells, all of which are fundamental for maintaining optimal tissue function and endocrine signaling.