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Hypothalamus-Pituitary-Gonadal Axis

Meaning

The Hypothalamus-Pituitary-Gonadal Axis, commonly abbreviated as the HPG axis, is a vital neuroendocrine control system that intricately coordinates the development, regulation, and function of the reproductive and sexual systems in humans. This interconnected feedback loop links the central nervous system’s command center with the peripheral hormone-producing glands. It is the fundamental physiological mechanism responsible for governing fertility, regulating libido, and maintaining secondary sexual characteristics throughout the lifespan.