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Hypothalamic Thermostat Calibration

Meaning

Hypothalamic Thermostat Calibration refers to the precise setting and regulation of the body’s core temperature set point, a crucial homeostatic function controlled by the preoptic area of the hypothalamus. This calibration is essential for initiating and maintaining restorative sleep, as a slight, controlled drop in core body temperature is a prerequisite for the transition into deep sleep stages. Dysfunction or ‘drift’ in this set point, often observed in perimenopause or with circadian misalignment, can lead to thermoregulatory disturbances like night sweats and subsequent sleep fragmentation, severely compromising hormonal recovery.