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Hypothalamic Regulation Feedback

Meaning

Hypothalamic Regulation Feedback describes the sophisticated, self-correcting communication loops, primarily the negative feedback mechanisms, that exist between the hypothalamus, the master regulator in the brain, and the peripheral endocrine glands. This precise regulatory system is the ultimate control center of the entire endocrine axis, dictating the pulsatile release of releasing hormones that subsequently control the pituitary and target glands, such as the thyroid, adrenals, and gonads. Precise feedback ensures that hormonal set-points are maintained within a narrow, optimal range, preventing pathological over- or under-production of critical, life-sustaining hormones.