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Hypophyseal Signal Transduction

Meaning

Hypophyseal Signal Transduction describes the intricate process by which chemical messengers, primarily releasing or inhibiting hormones from the hypothalamus, bind to receptors on pituitary (hypophyseal) cells, triggering a cascade of intracellular events that culminate in the secretion of pituitary hormones. This is the central communication step in all major neuroendocrine axes, including the HPA, HPT, and HPG axes. The integrity of this signal transduction is crucial for maintaining systemic hormonal homeostasis and ensuring appropriate endocrine responses to physiological demands.