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Hypoestrogenism

Meaning

Hypoestrogenism is a clinical state characterized by insufficient levels of circulating estrogen hormones, particularly estradiol, which is below the optimal physiological range. This deficiency commonly occurs after menopause, surgical removal of the ovaries, or in conditions that suppress ovarian function. The clinical sequelae include vasomotor symptoms, bone loss acceleration, and genitourinary atrophy. This condition requires careful clinical evaluation to mitigate long-term health risks.