What is the Origin of Hunger Signal?

This concept is foundational to the study of ingestive behavior and metabolism, linking the sensation of hunger to underlying physiological requirements. The identification of specific hormones mediating this signal revolutionized the understanding of appetite control.

What is the Mechanism of Hunger Signal?

The primary mechanism is mediated by the orexigenic hormone ghrelin, which is predominantly secreted by the stomach when it is empty. Ghrelin travels to the hypothalamus, where it acts on specific nuclei to stimulate the release of neuropeptide Y (NPY) and Agouti-related peptide (AgRP), intensely driving the sensation of hunger. Conversely, satiety hormones like leptin and PYY act to suppress this signal, maintaining a crucial, dynamic balance.

Hunger Signal ∞ Area

Hunger Signal

Meaning

The Hunger Signal is the complex neurohormonal message generated by the body to stimulate appetite and drive food-seeking behavior, ensuring adequate energy intake for metabolic needs. This sensation is a critical component of energy homeostasis, alerting the central nervous system to a state of caloric deficit or anticipated need. Disruptions to this signal can lead to dysregulated eating patterns and metabolic imbalance.