What is the Origin of Hunger Hormones?

This descriptive term arises from the clinical and physiological identification of hormones whose primary, measurable effect is the modulation of feeding behavior and energy balance. Their discovery provided a molecular basis for understanding the complex drive of hunger and the regulation of body weight.

What is the Mechanism of Hunger Hormones?

Ghrelin is predominantly secreted by the stomach when it is empty, traveling to the hypothalamus to activate orexigenic (appetite-stimulating) pathways. Conversely, Leptin is released from adipose tissue in proportion to body fat stores, acting on hypothalamic receptors to inhibit appetite and increase energy expenditure. The precise and coordinated signaling between these hormones and the brain dictates the overall set point for energy intake and body composition.

Hunger Hormones

Meaning

Hunger Hormones is a collective term referring to the specific peptide hormones that regulate appetite, satiety, and energy homeostasis within the body. These key endocrine messengers primarily include Ghrelin, which stimulates hunger, and Leptin, which signals satiety and energy sufficiency to the central nervous system. The balance and sensitivity of these hormones are crucial for weight management and metabolic health.