What is the Origin of Human Longevity Protocols?

This phrase is central to the emerging field of geroscience, which views aging not as an inevitable process but as a modifiable set of biological pathways. Its origin is tied to groundbreaking research into genetic pathways of aging, caloric restriction mimetics, and the therapeutic potential of senolytics. These protocols synthesize decades of biological research into actionable clinical strategies.

What is the Mechanism of Human Longevity Protocols?

The core mechanism involves the strategic modulation of conserved longevity pathways, including the mTOR, AMPK, and sirtuin pathways, which govern nutrient sensing and cellular stress response. Hormonal optimization is integral, ensuring adequate levels of Growth Hormone, DHEA, and sex steroids to maintain tissue anabolism and repair, counteracting age-related sarcopenia and bone loss. By enhancing autophagy and reducing the burden of senescent cells, these protocols promote systemic biological regeneration.

Human Longevity Protocols ∞ Area

Human Longevity Protocols

Meaning

Human Longevity Protocols are evidence-based, structured programs encompassing pharmacological, nutritional, lifestyle, and hormonal interventions designed to extend the period of healthy life, known as healthspan, and potentially overall lifespan. These protocols are clinically personalized, targeting the fundamental biological mechanisms of aging, such as cellular senescence, mitochondrial dysfunction, and genomic instability. The ultimate goal is to compress morbidity and sustain high-level physical and cognitive function for as long as possible.