What is the Origin of Human Healthspan?

This term originates from gerontology and longevity research, serving as a necessary counterpoint to simple life expectancy calculations. It emphasizes the functional capacity of organ systems, including metabolic and hormonal resilience, throughout aging. The concept promotes proactive intervention to delay morbidity.

What is the Mechanism of Human Healthspan?

Healthspan is mechanistically supported by maintaining genomic stability, optimizing mitochondrial efficiency, and preserving telomere integrity across tissues. Endocrine regulation, particularly optimal sex hormone and growth hormone signaling, plays a direct role in preserving muscle mass and bone density. Sustaining robust cellular repair mechanisms is key to extending this period of high-functioning life.

Human Healthspan

Meaning

Human Healthspan quantifies the duration of life spent in good health, free from the debilitating effects of chronic disease and significant functional decline. It is a metric distinct from chronological lifespan, focusing instead on physiological vitality and independence. Optimizing healthspan is a primary goal in preventative endocrinology and longevity science. This measurement reflects the quality of years lived.