The Human Engine is a conceptual framework used to describe the integrated totality of the body’s core physiological systems responsible for energy production, regulation, and maintenance, primarily encompassing the endocrine, metabolic, and mitochondrial systems. Viewing the body as an engine emphasizes the need for high-quality fuel, proper tuning, and consistent maintenance for sustained performance. It directs focus toward core physiological drivers.
Origin
This term is derived from engineering analogies applied to human physiology, popular in performance and longevity science circles. It provides a relatable metaphor for complex systemic interactions. The engine requires precise coordination between its components to function efficiently over time.
Mechanism
The engine’s primary function relies on efficient ATP generation via oxidative phosphorylation within the mitochondria, fueled by precise hormonal orchestration. Thyroid hormones govern the basal metabolic rate, while cortisol manages acute energy mobilization from storage depots. Optimization of the engine involves ensuring adequate substrate flow and minimizing inflammatory friction that impedes optimal energy conversion.
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