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Human Chorionic Gonadotropin (hCG)

Meaning

Human Chorionic Gonadotropin, or hCG, is a glycoprotein hormone produced initially by the syncytiotrophoblast cells of the implanted embryo and subsequently by the placenta throughout gestation. Physiologically, its critical role is to bind to the LH receptor on the corpus luteum, preventing its regression and thereby ensuring continuous progesterone production essential for maintaining the early pregnancy. Clinically, this hormone is the primary biomarker for pregnancy and is utilized therapeutically due to its structural and functional similarity to Luteinizing Hormone (LH).