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Hsd17b3

Meaning

Hsd17b3 is the gene that provides the blueprint for the enzyme 17-beta hydroxysteroid dehydrogenase type 3, a critical component of the steroidogenesis pathway. This enzyme is primarily active in the testes and is indispensable for the final step of potent androgen production. Mutations in this gene result in a specific disorder of sex development, highlighting its central role in male endocrine physiology.