What is the Origin of hs-CRP Inflammation Marker?

This marker is an acute-phase reactant synthesized by the liver, originating from the broader field of clinical immunology, but its clinical utility has expanded significantly into cardiometabolic and endocrine risk stratification. We use the high-sensitivity assay for subtle chronic changes that impact wellness.

What is the Mechanism of hs-CRP Inflammation Marker?

Chronic inflammation, indicated by high hs-CRP, generates cytokines that impair insulin receptor function, contributing to insulin resistance, and can also influence the synthesis and transport of critical steroid hormones. By implementing protocols to reduce this inflammatory burden, we often observe secondary improvements in metabolic flexibility and endocrine signaling fidelity.

hs-CRP Inflammation Marker ∞ Area

hs-CRP Inflammation Marker

Meaning

High-sensitivity C-Reactive Protein (hs-CRP) is a crucial biomarker reflecting systemic, low-grade inflammation, which significantly interferes with normal endocrine axis function, particularly insulin sensitivity and sex hormone receptor signaling. Elevated levels signal underlying physiological stress that clinicians must address.