Skip to main content

hs-CRP and Cognition

Meaning

hs-CRP and Cognition describes the significant clinical relationship between high-sensitivity C-Reactive Protein (hs-CRP), a systemic biomarker of low-grade inflammation, and various aspects of cognitive function, including memory, executive function, and processing speed. Elevated hs-CRP levels are associated with chronic, subclinical inflammation that can cross the blood-brain barrier, leading to neuroinflammation and neuronal damage over time. This correlation positions hs-CRP as a key indicator of systemic inflammatory load that can negatively impact neuroendocrine health and accelerate cognitive decline. Therapeutic strategies targeting inflammation are thus critical for cognitive preservation.