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HPG Axis Support Strategies

Meaning

HPG Axis Support Strategies are a collection of clinical interventions designed to optimize the function and signaling integrity of the Hypothalamic-Pituitary-Gonadal (HPG) axis, the central regulator of reproductive and sex hormone production. These strategies aim to address conditions like hypogonadism by encouraging the body’s endogenous production of hormones, such as testosterone and estrogen, rather than solely relying on exogenous replacement. Interventions often include specific peptides, selective estrogen receptor modulators, or lifestyle modifications tailored to restore feedback loop sensitivity. The primary clinical goal is to maintain or enhance fertility and overall hormonal homeostasis.