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HPG Axis Recovery Monitoring

Meaning

HPG Axis Recovery Monitoring is the systematic clinical assessment of the hypothalamic-pituitary-gonadal axis as it attempts to resume its natural, self-regulating function following a period of suppression, often induced by exogenous hormone administration or a pathological state. This meticulous process involves tracking key hormonal markers, including luteinizing hormone (LH), follicle-stimulating hormone (FSH), and endogenous sex steroids, over a defined period to confirm the restoration of the pulsatile release of gonadotropin-releasing hormone (GnRH). Successful recovery is paramount for long-term endocrine independence and fertility preservation, requiring a patient-specific, longitudinal approach.